Invertebrate nociception: behaviors, neurons and molecules.

Published

Journal Article (Review)

Genetic analysis of nociceptive behaviors in the nematode Caenorhabditis elegans and the fruit fly Drosophila melanogaster has led to the discovery of conserved sensory transduction channels and signaling molecules. These are embedded in neurons and circuits that generate responses to noxious signals. This article reviews the neurons and molecular mechanisms that underlie invertebrate nociception. We begin with the neurobiology of invertebrate nociception, and then focus on molecules with conserved functions in vertebrate nociception and sensory biology.

Full Text

Duke Authors

Cited Authors

  • Tobin, DM; Bargmann, CI

Published Date

  • October 2004

Published In

Volume / Issue

  • 61 / 1

Start / End Page

  • 161 - 174

PubMed ID

  • 15362159

Pubmed Central ID

  • 15362159

International Standard Serial Number (ISSN)

  • 0022-3034

Digital Object Identifier (DOI)

  • 10.1002/neu.20082

Language

  • eng

Conference Location

  • United States