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Controlling magnesium in surgery, intensive care, and beyond

Publication ,  Journal Article
Toffaletti, JG
Published in: Point of Care
June 1, 2007

In addition to the biochemical and physiological importance of magnesium, the increasing number of conditions associated with magnesium depletion, such as drug therapy and stress from surgery or trauma, have contributed toward increasing the clinical importance of detecting and correcting blood levels of magnesium. Orders for serum magnesium testing at our hospital have had astounding increases over the last 20 to 25 years, with more than 125,000 total magnesium measurements ordered in 2005. This report will cover recent findings in the following areas: • regulation of blood levels of magnesium; • the frequency of hypomagnesemia in critical care settings such as the intensive care unit and emergency department, in major surgery, and in metabolic disorders such as diabetes; • the cardiovascular and metabolic effects of magnesium depletion, such as arrhythmias, vasoconstriction, inflammation, hypercoagulability, insulin resistance, and electrolyte disturbances; and • the clinical benefits of magnesium supplementation in various settings. The diagnosis of magnesium deficiency will also be discussed with reference to total and ionized magnesium in blood, the magnesium retention test, and the role of a possible biomarker for detecting magnesium deficiency. © 2007 Lippincott Williams & Wilkins, Inc.

Duke Scholars

Published In

Point of Care

DOI

EISSN

1533-0303

ISSN

1533-029X

Publication Date

June 1, 2007

Volume

6

Issue

2

Start / End Page

129 / 133

Related Subject Headings

  • General Clinical Medicine
  • 1117 Public Health and Health Services
  • 1110 Nursing
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
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Toffaletti, J. G. (2007). Controlling magnesium in surgery, intensive care, and beyond. Point of Care, 6(2), 129–133. https://doi.org/10.1097/01.poc.0000271402.14936.9b
Toffaletti, J. G. “Controlling magnesium in surgery, intensive care, and beyond.” Point of Care 6, no. 2 (June 1, 2007): 129–33. https://doi.org/10.1097/01.poc.0000271402.14936.9b.
Toffaletti JG. Controlling magnesium in surgery, intensive care, and beyond. Point of Care. 2007 Jun 1;6(2):129–33.
Toffaletti, J. G. “Controlling magnesium in surgery, intensive care, and beyond.” Point of Care, vol. 6, no. 2, June 2007, pp. 129–33. Scopus, doi:10.1097/01.poc.0000271402.14936.9b.
Toffaletti JG. Controlling magnesium in surgery, intensive care, and beyond. Point of Care. 2007 Jun 1;6(2):129–133.

Published In

Point of Care

DOI

EISSN

1533-0303

ISSN

1533-029X

Publication Date

June 1, 2007

Volume

6

Issue

2

Start / End Page

129 / 133

Related Subject Headings

  • General Clinical Medicine
  • 1117 Public Health and Health Services
  • 1110 Nursing
  • 1103 Clinical Sciences