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Interpretation of blood lactate measurements in paediatric open-heart surgery and in extracorporeal membrane oxygenation.

Publication ,  Journal Article
Toffaletti, J; Hansell, D
Published in: Scand J Clin Lab Invest
July 1995

For the purpose of demonstrating both the clinical value and economic advantages of using blood lactate as a marker for haemodynamic instability, we present the clinical guidelines for when to measure blood lactate and how these measurements are interpreted in two clinical settings: following open-heart surgery for complex congenital heart disease, and in determining both the need for and the effectiveness of extracorporeal membrane oxygenation (ECMO). Several case histories are presented that demonstrate the conditions which can elevate blood lactate concentrations and the resulting therapeutic interventions, based on use of volume support, inotropic support, vasodilators, and/or ventilation, that can lead to a successful outcome in these patients. In one of the case histories a greatly elevated blood lactate apparently indicated that intracranial hemorrhage had occurred in a patient who later expired.

Duke Scholars

Published In

Scand J Clin Lab Invest

DOI

ISSN

0036-5513

Publication Date

July 1995

Volume

55

Issue

4

Start / End Page

301 / 307

Location

England

Related Subject Headings

  • Retrospective Studies
  • Postoperative Period
  • Oxygen Consumption
  • Lactic Acid
  • Lactates
  • Infant, Newborn
  • Humans
  • Heart Defects, Congenital
  • Female
  • Extracorporeal Membrane Oxygenation
 

Citation

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MLA
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Toffaletti, J., & Hansell, D. (1995). Interpretation of blood lactate measurements in paediatric open-heart surgery and in extracorporeal membrane oxygenation. Scand J Clin Lab Invest, 55(4), 301–307. https://doi.org/10.3109/00365519509104967
Toffaletti, J., and D. Hansell. “Interpretation of blood lactate measurements in paediatric open-heart surgery and in extracorporeal membrane oxygenation.Scand J Clin Lab Invest 55, no. 4 (July 1995): 301–7. https://doi.org/10.3109/00365519509104967.
Toffaletti, J., and D. Hansell. “Interpretation of blood lactate measurements in paediatric open-heart surgery and in extracorporeal membrane oxygenation.Scand J Clin Lab Invest, vol. 55, no. 4, July 1995, pp. 301–07. Pubmed, doi:10.3109/00365519509104967.
Journal cover image

Published In

Scand J Clin Lab Invest

DOI

ISSN

0036-5513

Publication Date

July 1995

Volume

55

Issue

4

Start / End Page

301 / 307

Location

England

Related Subject Headings

  • Retrospective Studies
  • Postoperative Period
  • Oxygen Consumption
  • Lactic Acid
  • Lactates
  • Infant, Newborn
  • Humans
  • Heart Defects, Congenital
  • Female
  • Extracorporeal Membrane Oxygenation