In vivo cardiac, acoustic-radiation-force-driven, shear wave velocimetry.

Journal Article (Journal Article)

Shear wave elasticity imaging (SWEI) was employed to track acoustic radiation force impulse (ARFI)-induced shear waves in the mid-myocardium of the left ventricular free wall (LVFW) of a beating canine heart. Shear waves were generated and tracked with a linear ultrasound transducer that was placed directly on the exposed epicardium. Acquisition was ECG-gated and coincided with the mid-diastolic portion of the cardiac cycle. Axial displacement profiles consistent with shear wave propagation were clearly evident in all SWEI acquisitions (i.e., those including an ARFI excitation); displacement data from control cases (i.e., sequences lacking an ARFI excitation) offered no evidence of shear wave propagation and yielded a peak absolute mean displacement below 0.31 microm after motion filtering. Shear wave velocity estimates ranged from 0.82 to 2.65 m/s and were stable across multiple heartbeats for the same interrogation region, with coefficients of variation less than 19% for all matched acquisitions. Variations in velocity estimates suggest a spatial dependence of shear wave velocity through the mid-myocardium of the LVFW, with velocity estimates changing, in limited cases, through depth and lateral position.

Full Text

Duke Authors

Cited Authors

  • Bouchard, RR; Hsu, SJ; Wolf, PD; Trahey, GE

Published Date

  • July 2009

Published In

Volume / Issue

  • 31 / 3

Start / End Page

  • 201 - 213

PubMed ID

  • 19771962

Pubmed Central ID

  • PMC2797484

Electronic International Standard Serial Number (EISSN)

  • 1096-0910

International Standard Serial Number (ISSN)

  • 0161-7346

Digital Object Identifier (DOI)

  • 10.1177/016173460903100305


  • eng