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Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid.

Publication ,  Journal Article
Fagerlin, A; Dillard, AJ; Smith, DM; Zikmund-Fisher, BJ; Pitsch, R; McClure, JB; Greene, S; Alford, SH; Nair, V; Hayes, DF; Wiese, C; Ubel, PA
Published in: Breast cancer research and treatment
June 2011

Although tamoxifen can prevent primary breast cancer, few women use it as a preventive measure. A second option, raloxifene, has recently been approved. The objective of the study was to determine women's interest in tamoxifen and raloxifene after reading a decision aid (DA) describing the risks and benefits of each medication. Women with 5-year risk of breast cancer ≥ 1.66 from two large health maintenance organizations were randomized to receive a DA versus usual care. After reading an on-line DA that discussed the risks and benefits of tamoxifen and raloxifene, women completed measures of risk perception, decisional conflict, behavioral intentions, and actual behavior related to tamoxifen and raloxifene. 3 months following the intervention, 8.1% of participants had looked for additional information about breast cancer prevention drugs, and 1.8% had talked to their doctor about tamoxifen and/or raloxifene. The majority, 54.7%, had decided to not take either drug, 0.5% had started raloxifene, and none had started tamoxifen. Participants were not particularly worried about taking tamoxifen or raloxifene and did not perceive significant benefits from taking these drugs. Over 50% did not perceive a change in their risk of getting breast cancer if they took tamoxifen or raloxifene. After reading a DA about tamoxifen and raloxifene, few women were interested in taking either breast cancer prevention drug.

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Published In

Breast cancer research and treatment

DOI

EISSN

1573-7217

ISSN

0167-6806

Publication Date

June 2011

Volume

127

Issue

3

Start / End Page

681 / 688

Related Subject Headings

  • Tamoxifen
  • Selective Estrogen Receptor Modulators
  • Raloxifene Hydrochloride
  • Patient Education as Topic
  • Oncology & Carcinogenesis
  • Middle Aged
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Female
  • Decision Making
 

Citation

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MLA
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Fagerlin, A., Dillard, A. J., Smith, D. M., Zikmund-Fisher, B. J., Pitsch, R., McClure, J. B., … Ubel, P. A. (2011). Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid. Breast Cancer Research and Treatment, 127(3), 681–688. https://doi.org/10.1007/s10549-011-1450-1
Fagerlin, Angela, Amanda J. Dillard, Dylan M. Smith, Brian J. Zikmund-Fisher, Rosemarie Pitsch, Jennifer B. McClure, Sarah Greene, et al. “Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid.Breast Cancer Research and Treatment 127, no. 3 (June 2011): 681–88. https://doi.org/10.1007/s10549-011-1450-1.
Fagerlin A, Dillard AJ, Smith DM, Zikmund-Fisher BJ, Pitsch R, McClure JB, et al. Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid. Breast cancer research and treatment. 2011 Jun;127(3):681–8.
Fagerlin, Angela, et al. “Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid.Breast Cancer Research and Treatment, vol. 127, no. 3, June 2011, pp. 681–88. Epmc, doi:10.1007/s10549-011-1450-1.
Fagerlin A, Dillard AJ, Smith DM, Zikmund-Fisher BJ, Pitsch R, McClure JB, Greene S, Alford SH, Nair V, Hayes DF, Wiese C, Ubel PA. Women's interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid. Breast cancer research and treatment. 2011 Jun;127(3):681–688.
Journal cover image

Published In

Breast cancer research and treatment

DOI

EISSN

1573-7217

ISSN

0167-6806

Publication Date

June 2011

Volume

127

Issue

3

Start / End Page

681 / 688

Related Subject Headings

  • Tamoxifen
  • Selective Estrogen Receptor Modulators
  • Raloxifene Hydrochloride
  • Patient Education as Topic
  • Oncology & Carcinogenesis
  • Middle Aged
  • Humans
  • Health Knowledge, Attitudes, Practice
  • Female
  • Decision Making