New insights into Chlamydia intracellular survival mechanisms.


Journal Article (Review)

Chlamydia sp. are responsible for a wide range of diseases of significant clinical and public health importance. In this review, we highlight how recent cellular and functional genomic approaches have significantly increased our knowledge of the pathogenic mechanisms used by these genetically intractable bacteria. As the extensive repertoire of chlamydial proteins that are translocated into the mammalian host is identified and characterized, a molecular understanding of how Chlamydiae co-opt host cellular functions and block innate immune pathways is beginning to emerge.

Full Text

Duke Authors

Cited Authors

  • Cocchiaro, JL; Valdivia, RH

Published Date

  • November 2009

Published In

Volume / Issue

  • 11 / 11

Start / End Page

  • 1571 - 1578

PubMed ID

  • 19673891

Pubmed Central ID

  • 19673891

Electronic International Standard Serial Number (EISSN)

  • 1462-5822

Digital Object Identifier (DOI)

  • 10.1111/j.1462-5822.2009.01364.x


  • eng

Conference Location

  • England