The response of depressed inpatients to isocarboxazid.

Published

Journal Article

Fifty-six inpatients with unipolar depression completed treatment with isocarboxazid. In comparing the differences between responders and nonresponders, it was found that psychomotor retardation, pathological guilt, daily persistence of unremitting symptoms, phobic anxiety, dexamethasone suppression test nonsuppression, and neuroticism were significantly more common among nonresponders. Reactivity of mood, blaming others, and extraversion were more common in responders. Total endogenous depression scores on the Newcastle 1, Newcastle 2, and Michigan scales were also significantly higher in nonresponders. Attained platelet monoamine oxidase inhibition was similar in both groups.

Full Text

Duke Authors

Cited Authors

  • Davidson, J; Lipper, S; Pelton, S; Miller, RD; Hammett, EB; Mahorney, S; Varia, IM

Published Date

  • April 1, 1988

Published In

Volume / Issue

  • 8 / 2

Start / End Page

  • 100 - 107

PubMed ID

  • 3372704

Pubmed Central ID

  • 3372704

Electronic International Standard Serial Number (EISSN)

  • 1533-712X

International Standard Serial Number (ISSN)

  • 0271-0749

Language

  • eng