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Multidisciplinary approaches in genetic studies of human aging and longevity

Publication ,  Journal Article
Tan, Q; Yashin, AI; Christensen, K; Jeune, B; De Benedictis, G; Kruse, TA; Vaupel, JW
Published in: Current Genomics
July 1, 2004

The amount of research on human aging and longevity has been growing rapidly in recent years. Multidisciplinary approaches, which integrate classic population genetics methods with the principles of epidemiological and demographic investigation, are emerging as powerful tools for disentangling the complex gene network which modulates human lifespan. We try to summarize the different approaches and discuss the various aspects concerning their applications in studies of human aging and longevity. We also discuss the significance of the newly emerging DNA chip technology and its implications by highlighting new research topics. In fact, with the entering of the post-genomic era, hints given by observational studies, and thus founded on statistical evidence, can be exploited to cast light upon biological pathways crucial in aging and longevity. © 2004 Bentham Science Publishers Ltd.

Duke Scholars

Published In

Current Genomics

DOI

ISSN

1389-2029

Publication Date

July 1, 2004

Volume

5

Issue

5

Start / End Page

409 / 416

Related Subject Headings

  • Developmental Biology
  • 3105 Genetics
  • 0604 Genetics
 

Citation

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Chicago
ICMJE
MLA
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Tan, Q., Yashin, A. I., Christensen, K., Jeune, B., De Benedictis, G., Kruse, T. A., & Vaupel, J. W. (2004). Multidisciplinary approaches in genetic studies of human aging and longevity. Current Genomics, 5(5), 409–416. https://doi.org/10.2174/1389202043349101
Tan, Q., A. I. Yashin, K. Christensen, B. Jeune, G. De Benedictis, T. A. Kruse, and J. W. Vaupel. “Multidisciplinary approaches in genetic studies of human aging and longevity.” Current Genomics 5, no. 5 (July 1, 2004): 409–16. https://doi.org/10.2174/1389202043349101.
Tan Q, Yashin AI, Christensen K, Jeune B, De Benedictis G, Kruse TA, et al. Multidisciplinary approaches in genetic studies of human aging and longevity. Current Genomics. 2004 Jul 1;5(5):409–16.
Tan, Q., et al. “Multidisciplinary approaches in genetic studies of human aging and longevity.” Current Genomics, vol. 5, no. 5, July 2004, pp. 409–16. Scopus, doi:10.2174/1389202043349101.
Tan Q, Yashin AI, Christensen K, Jeune B, De Benedictis G, Kruse TA, Vaupel JW. Multidisciplinary approaches in genetic studies of human aging and longevity. Current Genomics. 2004 Jul 1;5(5):409–416.
Journal cover image

Published In

Current Genomics

DOI

ISSN

1389-2029

Publication Date

July 1, 2004

Volume

5

Issue

5

Start / End Page

409 / 416

Related Subject Headings

  • Developmental Biology
  • 3105 Genetics
  • 0604 Genetics