Photothermal treatment of human carcinoma cells using liposome-encapsulated gold nanoshells

Journal Article (Journal Article)

We report the application of liposome-encapsulated gold nanoshells for in vitro photo-induced hyperthermia in human mammary carcinoma cells. In addition to evaluating their effects in vitro, we compared the application liposome-encapsulated gold nanoshells and free-standing gold nanoshells for NanoPhotoTherapy (NPT). NPT-induced hyperthermia was performed using a 785-nm near-infrared light from a diode laser and the in vitro effects were evaluated using nucleic acid molecular probes by fluorescence microscopy. Additionally, we monitored the effectiveness of NPT by detecting apoptosis via capase-9 activity. Copyright © 2005 Humana Press Inc. All rights of any nature whatsoever are reserved.

Full Text

Duke Authors

Cited Authors

  • Kasili, PM; Vo-Dinh, T

Published Date

  • December 1, 2005

Published In

Volume / Issue

  • 1 / 3

Start / End Page

  • 245 - 252

International Standard Serial Number (ISSN)

  • 1551-1286

Digital Object Identifier (DOI)

  • 10.1385/NBT:1:3:245

Citation Source

  • Scopus