Vibrational spectrum of strychnine: Detection at the nanogram level using a Raman microscope

Published

Journal Article

The complete vibrational spectra of strychnine is reported. Strychnine, a compound with medicinal value at the proper dosage, is also a potent toxin at certain concentration levels. Down to 5 ng of strychnine were detected from its spectrum using a microscope attached to a Raman spectrophotometer. The complete Raman and Fourier transform IR spectra were also recorded for positive identification. The prominent vibrational band wavenumbers useful as a reference source for the identification of strychnine in an emergency situation are discussed. The Raman spectra of a bulk sample and of a strychnine microcrystal are given to facilitate positive identification. The potential application of the vibrational analysis of strychnine for forensic diagnostics is discussed. Copyright © 1999 John Wiley & Sons, Ltd.

Duke Authors

Cited Authors

  • Anantha Narayanan, V; Stump, NA; Del Cul, GD; Vo-Dinh, T

Published Date

  • December 1, 1999

Published In

Volume / Issue

  • 30 / 6

Start / End Page

  • 435 - 439

International Standard Serial Number (ISSN)

  • 0377-0486

Citation Source

  • Scopus