Surface-enhanced Raman detection of nicotinamide in vitamin tablets

Journal Article (Journal Article)

Nicotinamide is analyzed quantitatively in vitamin tablets using surface-enhanced Raman scattering (SERS) on a silver-coated alumina substrate. Calibration curve of SERS signal intensity versus concentration of nicotinamide was established for quantitative analysis of this compound for detection at parts per million (ppm) level. SERS spectra of related compounds, nicotine, nicotinic acid, isonicotinic acid, and isonicotinamide were also recorded. Salient features of their spectra are compared and discussed. Copyright (C) 1998 Elsevier Science B.V.

Full Text

Duke Authors

Cited Authors

  • Pal, T; Anantha Narayanan, V; Stokes, DL; Vo-Dinh, T

Published Date

  • July 17, 1998

Published In

Volume / Issue

  • 368 / 1-2

Start / End Page

  • 21 - 28

International Standard Serial Number (ISSN)

  • 0003-2670

Digital Object Identifier (DOI)

  • 10.1016/S0003-2670(98)00192-5

Citation Source

  • Scopus