Surface-enhanced Raman gene probes.
Published
Journal Article
We report for the first time a new type of DNA gene probe based on surface-enhanced Raman scattering (SERS) label detection. The surface-enhanced Raman gene (SERG) probes do not require the use of radioactive labels and have great potential to provide both sensitivity and selectivity. The SERG probe can be used to detect DNA biotargets (e.g., gene sequences, bacteria, viral DNA fragments) via hybridization to DNA sequences complementary to that probe. The analytical figures of merit and its applications in environmental and biomedical areas are discussed.
Full Text
Duke Authors
Cited Authors
- Vo-Dinh, T; Houck, K; Stokes, DL
Published Date
- October 1994
Published In
Volume / Issue
- 66 / 20
Start / End Page
- 3379 - 3383
PubMed ID
- 7978314
Pubmed Central ID
- 7978314
Electronic International Standard Serial Number (EISSN)
- 1520-6882
International Standard Serial Number (ISSN)
- 0003-2700
Digital Object Identifier (DOI)
- 10.1021/ac00092a014
Language
- eng