The pharmacogenetics of coumarin therapy.
Publication
, Journal Article
Voora, D; McLeod, HL; Eby, C; Gage, BF
Published in: Pharmacogenomics
July 2005
Vitamin K antagonists (coumarins) are widely-used oral anticoagulants for the prevention of venous thromboembolism and strokes. Wide inter-individual variation in dose response and frequent bleeds characterize the initiation of coumarin therapy. Over the past 10 years both genetic and nongenetic determinants of coumarin dose response have been identified. A comprehensive pharmacogenetics approach to warfarin therapy has the potential to improve the safety and efficiency of warfarin initiation.
Duke Scholars
Published In
Pharmacogenomics
DOI
ISSN
1462-2416
Publication Date
July 2005
Volume
6
Issue
5
Start / End Page
503 / 513
Location
England
Related Subject Headings
- Warfarin
- Venous Thrombosis
- Stroke
- Pharmacology & Pharmacy
- Pharmacogenetics
- Models, Biological
- Humans
- Coumarins
- Blood Coagulation
- Anticoagulants
Citation
APA
Chicago
ICMJE
MLA
NLM
Voora, D., McLeod, H. L., Eby, C., & Gage, B. F. (2005). The pharmacogenetics of coumarin therapy. Pharmacogenomics, 6(5), 503–513. https://doi.org/10.2217/14622416.6.5.503
Voora, Deepak, Howard L. McLeod, Charles Eby, and Brian F. Gage. “The pharmacogenetics of coumarin therapy.” Pharmacogenomics 6, no. 5 (July 2005): 503–13. https://doi.org/10.2217/14622416.6.5.503.
Voora D, McLeod HL, Eby C, Gage BF. The pharmacogenetics of coumarin therapy. Pharmacogenomics. 2005 Jul;6(5):503–13.
Voora, Deepak, et al. “The pharmacogenetics of coumarin therapy.” Pharmacogenomics, vol. 6, no. 5, July 2005, pp. 503–13. Pubmed, doi:10.2217/14622416.6.5.503.
Voora D, McLeod HL, Eby C, Gage BF. The pharmacogenetics of coumarin therapy. Pharmacogenomics. 2005 Jul;6(5):503–513.
Published In
Pharmacogenomics
DOI
ISSN
1462-2416
Publication Date
July 2005
Volume
6
Issue
5
Start / End Page
503 / 513
Location
England
Related Subject Headings
- Warfarin
- Venous Thrombosis
- Stroke
- Pharmacology & Pharmacy
- Pharmacogenetics
- Models, Biological
- Humans
- Coumarins
- Blood Coagulation
- Anticoagulants