The role of radical prostatectomy in the management of prostatic adenocarcinoma - Biologic factors influencing the likelihood of local and systemic control

Journal Article (Journal Article)

Radical prostatectomy has been the mainstay of treatment for localized prostate cancer for over 50 years, but its value has been controversial. This report evaluates the impact of this therapeutic modality by assessing the value of various prognostic stratification systems in predicting the clinical outcome. Traditional stratifiers such as clinical stage, pathologic stage, and tumor grade are reviewed, as well as newer biologic parameters such as DNA content determined by automated flow cytometric analysis. Such newer predictors of response may enable an approach of selective enhanced aggressiveness in treating regional, advanced disease. © 1989 Springer-Verlag.

Full Text

Duke Authors

Cited Authors

  • Walther, PJ

Published Date

  • March 1, 1989

Published In

Volume / Issue

  • 7 / 1

Start / End Page

  • 38 - 44

Electronic International Standard Serial Number (EISSN)

  • 1433-8726

International Standard Serial Number (ISSN)

  • 0724-4983

Digital Object Identifier (DOI)

  • 10.1007/BF01576843

Citation Source

  • Scopus