Axonally translated SMADs link up BDNF and retrograde BMP signaling.
Publication
, Journal Article
Takatoh, J; Wang, F
Published in: Neuron
April 12, 2012
Axonal target-derived BMP and neurotrophin signaling are both known to regulate neuronal gene expression, differentiation, and axon growth. In this issue of Neuron, Ji and Jaffrey (2012) discovered that BMP-signaling endosomes depend on BDNF-induced axonal synthesis of SMADs to retrogradely regulate transcription in developing trigeminal neurons, providing a mechanism of integrating the two target-derived signals.
Duke Scholars
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Published In
Neuron
DOI
EISSN
1097-4199
Publication Date
April 12, 2012
Volume
74
Issue
1
Start / End Page
3 / 5
Location
United States
Related Subject Headings
- Trigeminal Ganglion
- Smad8 Protein
- Smad5 Protein
- Smad1 Protein
- Smad Proteins, Receptor-Regulated
- Neurology & Neurosurgery
- Cell Differentiation
- Axons
- Axonal Transport
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Takatoh, J., & Wang, F. (2012). Axonally translated SMADs link up BDNF and retrograde BMP signaling. Neuron, 74(1), 3–5. https://doi.org/10.1016/j.neuron.2012.03.012
Takatoh, Jun, and Fan Wang. “Axonally translated SMADs link up BDNF and retrograde BMP signaling.” Neuron 74, no. 1 (April 12, 2012): 3–5. https://doi.org/10.1016/j.neuron.2012.03.012.
Takatoh J, Wang F. Axonally translated SMADs link up BDNF and retrograde BMP signaling. Neuron. 2012 Apr 12;74(1):3–5.
Takatoh, Jun, and Fan Wang. “Axonally translated SMADs link up BDNF and retrograde BMP signaling.” Neuron, vol. 74, no. 1, Apr. 2012, pp. 3–5. Pubmed, doi:10.1016/j.neuron.2012.03.012.
Takatoh J, Wang F. Axonally translated SMADs link up BDNF and retrograde BMP signaling. Neuron. 2012 Apr 12;74(1):3–5.
Published In
Neuron
DOI
EISSN
1097-4199
Publication Date
April 12, 2012
Volume
74
Issue
1
Start / End Page
3 / 5
Location
United States
Related Subject Headings
- Trigeminal Ganglion
- Smad8 Protein
- Smad5 Protein
- Smad1 Protein
- Smad Proteins, Receptor-Regulated
- Neurology & Neurosurgery
- Cell Differentiation
- Axons
- Axonal Transport
- Animals