Visual event-related potentials under different interstimulus intervals in Parkinson's disease: Relation to motor disability, WAIS-R, and regional cerebral blood flow

Journal Article

We have introduced S1-S2 paradigm (task S) as well as oddball paradigm (task O) visual event-related potentials (ERPs) under different interstimulus intervals (ISIs) in Parkinson's disease (PD). ERP measurements were correlated with motor disability, WAIS-R, and regional cerebral blood flow (rCBF). The 'group' influence was characterized by longer latency for P300, N200, and reaction time and decreased P300 amplitude in PD. Both P300 latency and reaction time during task O showed significantly longer latency in longer ISI condition. Our results revealed 'ISI' influence on ERPs during task S and significant correlation between ERPs and rCBF in task S. © 2004 Elsevier Ltd. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Li, M; Kuroiwa, Y; Wang, L; Kamitani, T; Omoto, S; Hayashi, E; Takahashi, T; Suzuki, Y; Koyano, S; Ikegami, T; Matsubara, S

Published Date

  • 2005

Published In

  • Parkinsonism and Related Disorders

Volume / Issue

  • 11 / 4

Start / End Page

  • 209 - 219

PubMed ID

  • 15878581

Digital Object Identifier (DOI)

  • 10.1016/j.parkreldis.2004.11.004