Where PI3K/Akt meets Smads: the crosstalk determines human embryonic stem cell fate.

Journal Article (Journal Article)

Coordinated interactions between signaling networks govern the balance of cell fate decisions in human embryonic stem cells. In this issue, Singh et al. (2012) report that PI3K/Akt signaling switches Activin/Smad activity between pro-self-renewal and prodifferentiation by regulating ERK and GSK3β/β-catenin signaling.

Full Text

Duke Authors

Cited Authors

  • Chen, Y-G; Li, Z; Wang, X-F

Published Date

  • March 2, 2012

Published In

Volume / Issue

  • 10 / 3

Start / End Page

  • 231 - 232

PubMed ID

  • 22385648

Pubmed Central ID

  • PMC3586792

Electronic International Standard Serial Number (EISSN)

  • 1875-9777

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2012.02.008


  • eng

Conference Location

  • United States