Finale: the last minutes of Smads.

Journal Article (Journal Article)

TGF-beta ligands induce phosphorylation of receptor-activated Smads at both the C-terminal tail and the linker region. Two papers from Massagué and colleagues (Alarcón et al., 2009; Gao et al., 2009) reveal a dual role for this linker phosphorylation, which is required for activation of Smads and for their degradation.

Full Text

Duke Authors

Cited Authors

  • Chen, Y-G; Wang, X-F

Published Date

  • November 13, 2009

Published In

Volume / Issue

  • 139 / 4

Start / End Page

  • 658 - 660

PubMed ID

  • 19914161

Electronic International Standard Serial Number (EISSN)

  • 1097-4172

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2009.10.038


  • eng

Conference Location

  • United States