From breast to the brain: unraveling the puzzle of metastasis organotropism.

Journal Article (Journal Article)

Metastatic colonization of different target organs is a highly selective process that depends on specialized properties of tumor cells. In a recent Nature paper, Massagué and colleagues built on their earlier success in functional genomic analysis of breast cancer metastasis to bone and lung and reported the identification of breast cancer brain metastasis genes, highlighting the importance of the stromal environment in the development of organ-specific metastasis.

Full Text

Duke Authors

Cited Authors

  • Hu, G; Kang, Y; Wang, X-F

Published Date

  • October 2009

Published In

Volume / Issue

  • 1 / 1

Start / End Page

  • 3 - 5

PubMed ID

  • 19633017

Electronic International Standard Serial Number (EISSN)

  • 1759-4685

Digital Object Identifier (DOI)

  • 10.1093/jmcb/mjp005


  • eng

Conference Location

  • United States