Development of a 4D dosimetry simulation system in radiotherapy


Journal Article

4D CT image sets are used to encode patient-organ motion and to calculate the dose delivered during each respiratory phase. The dose-per-phase is summarised to the total dose via deformable registration. The system incorporates the actual beam parameters and synchronises the beam motion (e.g., gantry/MLC motion of the DARC and MLC motion of the IMRT) to the patient's respiratory motion. Furthermore, this system incorporates different treatment techniques such as 3D conformal (3DCRT), dynamic arc (DARC), and Intensity-Modulated Radiation Therapy (IMRT), thus allows better understanding of organ motion effect on dose delivery, treatment techniques and corresponding optimal margins. Copyright © 2012 Inderscience Enterprises Ltd.

Full Text

Duke Authors

Cited Authors

  • Wu, QJ; Thongphiew, D; Wang, Z; Willett, C; Marks, L; Yin, FF

Published Date

  • May 1, 2012

Published In

Volume / Issue

  • 8 / 2-3

Start / End Page

  • 230 - 244

Electronic International Standard Serial Number (EISSN)

  • 1752-6426

International Standard Serial Number (ISSN)

  • 1752-6418

Digital Object Identifier (DOI)

  • 10.1504/IJBET.2012.046088

Citation Source

  • Scopus