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iDQC anisotropy map imaging for tumor tissue characterization in vivo.

Publication ,  Journal Article
Branca, RT; Chen, YM; Mouraviev, V; Galiana, G; Jenista, ER; Kumar, C; Leuschner, C; Warren, WS
Published in: Magnetic resonance in medicine
April 2009

Intermolecular double quantum coherences (iDQCs), signals that result from simultaneous transitions of two or more separated spins, are known to produce images that are highly sensitive to subvoxel structure, particularly local anisotropy. Here we demonstrate how iDQCs signal can be used to efficiently detect the anisotropy created in breast tumor tissues and prostate tumor tissues by targeted (LHRH-conjugated) superparamagnetic nanoparticles (SPIONs), thereby distinguishing the necrotic area from the surrounding tumor tissue.

Duke Scholars

Published In

Magnetic resonance in medicine

DOI

EISSN

1522-2594

ISSN

0740-3194

Publication Date

April 2009

Volume

61

Issue

4

Start / End Page

937 / 943

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Prostatic Neoplasms
  • Nuclear Medicine & Medical Imaging
  • Mice, Nude
  • Mice
  • Male
  • Magnetics
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Branca, R. T., Chen, Y. M., Mouraviev, V., Galiana, G., Jenista, E. R., Kumar, C., … Warren, W. S. (2009). iDQC anisotropy map imaging for tumor tissue characterization in vivo. Magnetic Resonance in Medicine, 61(4), 937–943. https://doi.org/10.1002/mrm.21925
Branca, Rosa T., Yuming M. Chen, Vladimir Mouraviev, Gigi Galiana, Elizabeth R. Jenista, Challa Kumar, Carola Leuschner, and Warren S. Warren. “iDQC anisotropy map imaging for tumor tissue characterization in vivo.Magnetic Resonance in Medicine 61, no. 4 (April 2009): 937–43. https://doi.org/10.1002/mrm.21925.
Branca RT, Chen YM, Mouraviev V, Galiana G, Jenista ER, Kumar C, et al. iDQC anisotropy map imaging for tumor tissue characterization in vivo. Magnetic resonance in medicine. 2009 Apr;61(4):937–43.
Branca, Rosa T., et al. “iDQC anisotropy map imaging for tumor tissue characterization in vivo.Magnetic Resonance in Medicine, vol. 61, no. 4, Apr. 2009, pp. 937–43. Epmc, doi:10.1002/mrm.21925.
Branca RT, Chen YM, Mouraviev V, Galiana G, Jenista ER, Kumar C, Leuschner C, Warren WS. iDQC anisotropy map imaging for tumor tissue characterization in vivo. Magnetic resonance in medicine. 2009 Apr;61(4):937–943.
Journal cover image

Published In

Magnetic resonance in medicine

DOI

EISSN

1522-2594

ISSN

0740-3194

Publication Date

April 2009

Volume

61

Issue

4

Start / End Page

937 / 943

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Prostatic Neoplasms
  • Nuclear Medicine & Medical Imaging
  • Mice, Nude
  • Mice
  • Male
  • Magnetics
  • Magnetic Resonance Imaging
  • Image Interpretation, Computer-Assisted