Label-free in vivo optical imaging of microvasculature and oxygenation level.

Journal Article (Letter)

The ability to perform high-resolution imaging of microvasculature and its oxygenation is very important in studying early tumor development. Toward this goal, we improved upon our excited state absorption (ESA)-based imaging technique to allow us to not only image hemoglobin directly but also differentiate between oxy- and deoxyhemoglobin in tissue. We demonstrate the separation of arterioles from venules in a live nude mouse ear using our imaging technique.

Full Text

Duke Authors

Cited Authors

  • Fu, D; Matthews, TE; Ye, T; Piletic, IR; Warren, WS

Published Date

  • July 2008

Published In

Volume / Issue

  • 13 / 4

Start / End Page

  • 040503 -

PubMed ID

  • 19021307

Electronic International Standard Serial Number (EISSN)

  • 1560-2281

International Standard Serial Number (ISSN)

  • 1083-3668

Digital Object Identifier (DOI)

  • 10.1117/1.2968260


  • eng