High-efficiency diffuse Raman spectroscopy through a fiber bundle.
Journal Article (Journal Article)
Conventional spectrometers are limited in the amount of light they accept because of the requirement for narrow input apertures. A trade-off must generally be made between spectral resolution and input aperture width. This is especially a problem for performing spectroscopy on diffuse sources, such as with tissue, from which signal light has a broad spatial distribution. We introduce a method for achieving good spectral resolution from a fiber bundle input. The image of a fiber bundle has a characteristic structure. By distorting this image optically, we generate a pseudo-orthogonal intensity mask at the input of the spectrometer. The pseudo-orthogonal properties of the mask then allow decoupling at the detector plane of wavelength from spatial position. As long as the distorted image of the fiber bundle is well known, a spectrum can be recovered with spectral resolution equivalent to that of a conventional slit-based spectrometer. We demonstrate successful recovery of narrowly spaced spectral features as well as Raman spectra from a highly scattering sample with this method. This method enables probes with much higher throughputs and add fiber bundle-based spectroscopy to endoscopic designs.
Full Text
Duke Authors
Cited Authors
- Matthews, TE; Wax, A
Published Date
- January 2012
Published In
- Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference
Volume / Issue
- 2012 /
Start / End Page
- 1181 - 1183
PubMed ID
- 23366108
Electronic International Standard Serial Number (EISSN)
- 2694-0604
International Standard Serial Number (ISSN)
- 2375-7477
Digital Object Identifier (DOI)
- 10.1109/embc.2012.6346147
Language
- eng