Phase-sensitive OCT imaging of multiple nanoparticle species using spectrally multiplexed single pulse photothermal excitation.


Journal Article

We apply phase-sensitive optical coherence tomography to image multiple nanoparticle species with two excitation wavelengths matched to their distinct absorption peaks. Using different modulation frequencies, multiple species collocated within the sample can be distinguished. In addition, we characterize single-pulse excitation schemes as a method to minimize bulk heating of the sample. We demonstrate this new scheme with B-mode photothermal measurements of tissue phantoms.

Full Text

Duke Authors

Cited Authors

  • Kim, S; Rinehart, MT; Park, H; Zhu, Y; Wax, A

Published Date

  • October 2012

Published In

Volume / Issue

  • 3 / 10

Start / End Page

  • 2579 - 2586

PubMed ID

  • 23082297

Pubmed Central ID

  • 23082297

Electronic International Standard Serial Number (EISSN)

  • 2156-7085

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/boe.3.002579


  • eng