Determining size, shape, and orientation of non-spherical scatterers using the fiber optic interferometric two-dimensional scattering (FITS) system

Journal Article

Angle-resolved scattering measurements have shown promise as a method of detecting neoplasia and analyzing cellular structure. Recently we have developed new systems for interferometric measurement of two-dimensional, depth resolved scattered fields with excellent depth resolution and polarization sensitivity. We present inverse analysis of oriented ensembles of micro-spheroidal phantoms and cells showing sub-wavelength accuracy in size and shape determination, and additionally precise estimates of scatterer orientation. Finally we show that inverse fits provided are essentially free of multiple solutions over a wide range of possible scatterer sizes and shapes. © 2011 SPIE.

Full Text

Duke Authors

Cited Authors

  • Giacomelli, M; Zhu, Y; Lee, J; Wax, A

Published Date

  • March 31, 2011

Published In

Volume / Issue

  • 7907 /

International Standard Serial Number (ISSN)

  • 1605-7422

Digital Object Identifier (DOI)

  • 10.1117/12.874081

Citation Source

  • Scopus