Genetics of coagulation: considerations for cardiac surgery.
Published
Journal Article (Review)
Genetic variants in the coagulation system have been known since antiquity. Today, because of modern improvements in diagnosis and medical management, the clinician is likely to encounter a spectrum of coagulation factor deficiencies and identified polymorphic variants in the surgical population. Because perioperative hemorrhagic and thrombotic complications are potentially serious, it is important to understand the role that these defects and variants may play in predicting risk and optimizing patient management. The implications of coagulation genetics on the perioperative management of the cardiac surgery patient are reviewed.
Full Text
Duke Authors
Cited Authors
- Morozowich, ST; Donahue, BS; Welsby, IJ
Published Date
- December 2006
Published In
Volume / Issue
- 10 / 4
Start / End Page
- 297 - 313
PubMed ID
- 17200088
Pubmed Central ID
- 17200088
International Standard Serial Number (ISSN)
- 1089-2532
Digital Object Identifier (DOI)
- 10.1177/1089253206294345
Language
- eng
Conference Location
- United States