50 million years of genomic stasis in endosymbiotic bacteria.
Publication
, Journal Article
Tamas, I; Klasson, L; Canbäck, B; Näslund, AK; Eriksson, A-S; Wernegreen, JJ; Sandström, JP; Moran, NA; Andersson, SGE
Published in: Science (New York, N.Y.)
June 2002
Comparison of two fully sequenced genomes of Buchnera aphidicola, the obligate endosymbionts of aphids, reveals the most extreme genome stability to date: no chromosome rearrangements or gene acquisitions have occurred in the past 50 to 70 million years, despite substantial sequence evolution and the inactivation and loss of individual genes. In contrast, the genomes of their closest free-living relatives, Escherichia coli and Salmonella spp., are more than 2000-fold more labile in content and gene order. The genomic stasis of B. aphidicola, likely attributable to the loss of phages, repeated sequences, and recA, indicates that B. aphidicola is no longer a source of ecological innovation for its hosts.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Science (New York, N.Y.)
DOI
EISSN
1095-9203
ISSN
0036-8075
Publication Date
June 2002
Volume
296
Issue
5577
Start / End Page
2376 / 2379
Related Subject Headings
- Symbiosis
- Species Specificity
- Salmonella typhimurium
- Repetitive Sequences, Nucleic Acid
- Recombination, Genetic
- Pseudogenes
- Operon
- Mutation
- Molecular Sequence Data
- Genome, Bacterial
Citation
APA
Chicago
ICMJE
MLA
NLM
Tamas, I., Klasson, L., Canbäck, B., Näslund, A. K., Eriksson, A.-S., Wernegreen, J. J., … Andersson, S. G. E. (2002). 50 million years of genomic stasis in endosymbiotic bacteria. Science (New York, N.Y.), 296(5577), 2376–2379. https://doi.org/10.1126/science.1071278
Tamas, Ivica, Lisa Klasson, Björn Canbäck, A Kristina Näslund, Ann-Sofie Eriksson, Jennifer J. Wernegreen, Jonas P. Sandström, Nancy A. Moran, and Siv G. E. Andersson. “50 million years of genomic stasis in endosymbiotic bacteria.” Science (New York, N.Y.) 296, no. 5577 (June 2002): 2376–79. https://doi.org/10.1126/science.1071278.
Tamas I, Klasson L, Canbäck B, Näslund AK, Eriksson A-S, Wernegreen JJ, et al. 50 million years of genomic stasis in endosymbiotic bacteria. Science (New York, NY). 2002 Jun;296(5577):2376–9.
Tamas, Ivica, et al. “50 million years of genomic stasis in endosymbiotic bacteria.” Science (New York, N.Y.), vol. 296, no. 5577, June 2002, pp. 2376–79. Epmc, doi:10.1126/science.1071278.
Tamas I, Klasson L, Canbäck B, Näslund AK, Eriksson A-S, Wernegreen JJ, Sandström JP, Moran NA, Andersson SGE. 50 million years of genomic stasis in endosymbiotic bacteria. Science (New York, NY). 2002 Jun;296(5577):2376–2379.
Published In
Science (New York, N.Y.)
DOI
EISSN
1095-9203
ISSN
0036-8075
Publication Date
June 2002
Volume
296
Issue
5577
Start / End Page
2376 / 2379
Related Subject Headings
- Symbiosis
- Species Specificity
- Salmonella typhimurium
- Repetitive Sequences, Nucleic Acid
- Recombination, Genetic
- Pseudogenes
- Operon
- Mutation
- Molecular Sequence Data
- Genome, Bacterial