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Biological functions and transcriptional targets of CaRF in neurons.

Publication ,  Journal Article
West, AE
Published in: Cell Calcium
May 2011

Calcium-response factor (CaRF) is a unique DNA-binding protein first recognized as a transcription factor for its role in modulating transcription of the gene encoding Brain-Derived Neurotrophic Factor (BDNF) in neurons. Here I review evidence for the biological functions and transcriptional targets of CaRF in the brain and discuss potential mechanisms by which calcium-activated signaling pathways may modulate CaRF-dependent transcription. These data paint an emerging picture of CaRF as a regulatory nexus for signaling pathways that control aspects of synaptic development and neuronal function.

Duke Scholars

Published In

Cell Calcium

DOI

EISSN

1532-1991

Publication Date

May 2011

Volume

49

Issue

5

Start / End Page

290 / 295

Location

Netherlands

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Neurons
  • Mice
  • Calcium Signaling
  • Brain-Derived Neurotrophic Factor
  • Biochemistry & Molecular Biology
  • Animals
  • 3208 Medical physiology
  • 3101 Biochemistry and cell biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
West, A. E. (2011). Biological functions and transcriptional targets of CaRF in neurons. Cell Calcium, 49(5), 290–295. https://doi.org/10.1016/j.ceca.2011.04.003
West, Anne E. “Biological functions and transcriptional targets of CaRF in neurons.Cell Calcium 49, no. 5 (May 2011): 290–95. https://doi.org/10.1016/j.ceca.2011.04.003.
West AE. Biological functions and transcriptional targets of CaRF in neurons. Cell Calcium. 2011 May;49(5):290–5.
West, Anne E. “Biological functions and transcriptional targets of CaRF in neurons.Cell Calcium, vol. 49, no. 5, May 2011, pp. 290–95. Pubmed, doi:10.1016/j.ceca.2011.04.003.
West AE. Biological functions and transcriptional targets of CaRF in neurons. Cell Calcium. 2011 May;49(5):290–295.
Journal cover image

Published In

Cell Calcium

DOI

EISSN

1532-1991

Publication Date

May 2011

Volume

49

Issue

5

Start / End Page

290 / 295

Location

Netherlands

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Neurons
  • Mice
  • Calcium Signaling
  • Brain-Derived Neurotrophic Factor
  • Biochemistry & Molecular Biology
  • Animals
  • 3208 Medical physiology
  • 3101 Biochemistry and cell biology