Reaction based fluorescent probes for hydrogen sulfide.


Journal Article

A reaction based fluorescence turn-on strategy for hydrogen sulfide (H(2)S) was developed. This strategy was based on a H(2)S-specific Michael addition-cyclization sequence. Other biological thiols such as cysteine and glutathione did not pursue the reaction and therefore did not turn on the fluorescence/consume the substrates. The probes showed good selectivity and sensitivity for hydrogen sulfide.

Full Text

Cited Authors

  • Liu, C; Peng, B; Li, S; Park, C-M; Whorton, AR; Xian, M

Published Date

  • April 9, 2012

Published In

Volume / Issue

  • 14 / 8

Start / End Page

  • 2184 - 2187

PubMed ID

  • 22486842

Pubmed Central ID

  • 22486842

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol3008183


  • eng