Mechanistic analysis of gold(I)-catalyzed intramolecular allene hydroalkoxylation reveals an off-cycle bis(gold) vinyl species and reversible C-O bond formation.

Journal Article (Journal Article)

Mechanistic investigation of gold(I)-catalyzed intramolecular allene hydroalkoxylation established a mechanism involving rapid and reversible C-O bond formation followed by turnover-limiting protodeauration from a mono(gold) vinyl complex. This on-cycle pathway competes with catalyst aggregation and formation of an off-cycle bis(gold) vinyl complex.

Full Text

Duke Authors

Cited Authors

  • Brown, TJ; Weber, D; Gagné, MR; Widenhoefer, RA

Published Date

  • June 2012

Published In

Volume / Issue

  • 134 / 22

Start / End Page

  • 9134 - 9137

PubMed ID

  • 22621418

Pubmed Central ID

  • PMC3433713

Electronic International Standard Serial Number (EISSN)

  • 1520-5126

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja303844h


  • eng