Room temperature hydroamination of N-alkenyl ureas catalyzed by a gold(i) N-heterocyclic carbene complex.

Journal Article (Journal Article)

[Structure: see text] Treatment of an N-4-pentenyl or N-5-hexenyl urea with a catalytic 1:1 mixture of a gold(I) N,N-diaryl imidazol-2-ylidine complex and AgOTf at or near room temperature leads to intramolecular exo-hydroamination to form the corresponding nitrogen heterocycle in excellent yield.

Full Text

Duke Authors

Cited Authors

  • Bender, CF; Widenhoefer, RA

Published Date

  • November 2006

Published In

Volume / Issue

  • 8 / 23

Start / End Page

  • 5303 - 5305

PubMed ID

  • 17078703

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol062107i


  • eng