Programmable diagnostic devices made from paper and tape

Journal Article

This paper describes three-dimensional microfluidic paper-based analytical devices (3-D PADs) that can be programmed (postfabrication) by the user to generate multiple patterns of flow through them. These devices are programmed by pressing single-use 'on' buttons, using a stylus or a ballpoint pen. Pressing a button closes a small space (gap) between two vertically aligned microfluidic channels, and allows fluids to wick from one channel to the other. These devices are simple to fabricate, and are made entirely out of paper and double-sided adhesive tape. Programmable devices expand the capabilities of PADs and provide a simple method for controlling the movement of fluids in paper-based channels. They are the conceptual equivalent of field-programmable gate arrays (FPGAs) widely used in electronics. © 2010 The Royal Society of Chemistry.

Full Text

Duke Authors

Cited Authors

  • Martinez, AW; Phillips, ST; Nie, Z; Cheng, CM; Carrilho, E; Wiley, BJ; Whitesides, GM

Published Date

  • 2010

Published In

Volume / Issue

  • 10 / 19

Start / End Page

  • 2499 - 2504

International Standard Serial Number (ISSN)

  • 1473-0197

Digital Object Identifier (DOI)

  • 10.1039/c0lc00021c