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Programmable diagnostic devices made from paper and tape.

Publication ,  Journal Article
Martinez, AW; Phillips, ST; Nie, Z; Cheng, C-M; Carrilho, E; Wiley, BJ; Whitesides, GM
Published in: Lab on a chip
October 2010

This paper describes three-dimensional microfluidic paper-based analytical devices (3-D microPADs) that can be programmed (postfabrication) by the user to generate multiple patterns of flow through them. These devices are programmed by pressing single-use 'on' buttons, using a stylus or a ballpoint pen. Pressing a button closes a small space (gap) between two vertically aligned microfluidic channels, and allows fluids to wick from one channel to the other. These devices are simple to fabricate, and are made entirely out of paper and double-sided adhesive tape. Programmable devices expand the capabilities of microPADs and provide a simple method for controlling the movement of fluids in paper-based channels. They are the conceptual equivalent of field-programmable gate arrays (FPGAs) widely used in electronics.

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Published In

Lab on a chip

DOI

EISSN

1473-0189

ISSN

1473-0197

Publication Date

October 2010

Volume

10

Issue

19

Start / End Page

2499 / 2504

Related Subject Headings

  • Reagent Kits, Diagnostic
  • Paper
  • Microfluidic Analytical Techniques
  • Flow Injection Analysis
  • Equipment Failure Analysis
  • Equipment Design
  • Disposable Equipment
  • Analytical Chemistry
  • 40 Engineering
  • 34 Chemical sciences
 

Citation

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Martinez, A. W., Phillips, S. T., Nie, Z., Cheng, C.-M., Carrilho, E., Wiley, B. J., & Whitesides, G. M. (2010). Programmable diagnostic devices made from paper and tape. Lab on a Chip, 10(19), 2499–2504. https://doi.org/10.1039/c0lc00021c
Martinez, Andres W., Scott T. Phillips, Zhihong Nie, Chao-Min Cheng, Emanuel Carrilho, Benjamin J. Wiley, and George M. Whitesides. “Programmable diagnostic devices made from paper and tape.Lab on a Chip 10, no. 19 (October 2010): 2499–2504. https://doi.org/10.1039/c0lc00021c.
Martinez AW, Phillips ST, Nie Z, Cheng C-M, Carrilho E, Wiley BJ, et al. Programmable diagnostic devices made from paper and tape. Lab on a chip. 2010 Oct;10(19):2499–504.
Martinez, Andres W., et al. “Programmable diagnostic devices made from paper and tape.Lab on a Chip, vol. 10, no. 19, Oct. 2010, pp. 2499–504. Epmc, doi:10.1039/c0lc00021c.
Martinez AW, Phillips ST, Nie Z, Cheng C-M, Carrilho E, Wiley BJ, Whitesides GM. Programmable diagnostic devices made from paper and tape. Lab on a chip. 2010 Oct;10(19):2499–2504.
Journal cover image

Published In

Lab on a chip

DOI

EISSN

1473-0189

ISSN

1473-0197

Publication Date

October 2010

Volume

10

Issue

19

Start / End Page

2499 / 2504

Related Subject Headings

  • Reagent Kits, Diagnostic
  • Paper
  • Microfluidic Analytical Techniques
  • Flow Injection Analysis
  • Equipment Failure Analysis
  • Equipment Design
  • Disposable Equipment
  • Analytical Chemistry
  • 40 Engineering
  • 34 Chemical sciences