Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers.


Journal Article (Review)

Although still in very early stages of clinical development, the combination of antiangiogenics with contemporary chemoradiotherapy regimens has emerged as a feasible and promising approach to many cancers. We review the rationale and the current understanding of antiangiogenics and their therapeutic potential in combination with chemoradiotherapy. Finally, we offer a perspective on future research directions aimed at making this complex therapeutic approach successful in the clinic.

Full Text

Duke Authors

Cited Authors

  • Duda, DG; Jain, RK; Willett, CG

Published Date

  • September 10, 2007

Published In

Volume / Issue

  • 25 / 26

Start / End Page

  • 4033 - 4042

PubMed ID

  • 17827451

Pubmed Central ID

  • 17827451

Electronic International Standard Serial Number (EISSN)

  • 1527-7755

Digital Object Identifier (DOI)

  • 10.1200/JCO.2007.11.3985


  • eng

Conference Location

  • United States