Intraoperatic electron beam irradiation in pancreatic cancer.

Published online

Journal Article (Review)

Intraoperative electron beam radiation therapy (IOERT) is a technique in which a single high fraction radiation treatment is administered at the time of surgery. Using IOERT, the total radiation dose delivered to a tumor can be increased since sensitive normal tissues are removed from the radiation field during the surgical procedure. Furthermore, while the biologic effectiveness of this single fraction is incompletely understood, it is believed to be equivalent to that of a dose at least two times greater given by means of conventional fractionation. IOERT may improve local tumor control in patients with resectable or locally advanced pancreatic cancer. At the Massachusetts General Hospital (MGH), IOERT is being investigated in the management of pancreatic cancer as a boost treatment in combination with external beam radiation, surgery and chemotherapy.

Full Text

Duke Authors

Cited Authors

  • Willett, CG; Warshaw, AL

Published Date

  • November 15, 1998

Published In

Volume / Issue

  • 3 /

Start / End Page

  • E207 - E213

PubMed ID

  • 9820742

Pubmed Central ID

  • 9820742

International Standard Serial Number (ISSN)

  • 1093-9946

Digital Object Identifier (DOI)

  • 10.2741/a379


  • eng

Conference Location

  • United States