Sphincter preservation in rectal cancer. Local excision followed by postoperative radiation therapy.

Journal Article (Journal Article;Review)

The management of distal rectal cancer is in evolution. Although abdominoperineal resection has been long regarded as the definitive treatment of distal rectal cancer, it is associated with significant morbidity--loss of anorectal function with a permanent colostomy and a high incidence of sexual and genitourinary dysfunction. To overcome these limitations, innovative efforts are underway studying the feasibility and efficacy of a variety of sphincter-preserving operations, usually in combination with radiation therapy and chemotherapy. Local excision procedures with adjuvant therapy represent one such treatment strategy that attempts to optimize local control and survival with preservation of sphincter integrity. This article summarizes the current role of local excision and postoperative irradiation and chemotherapy for patients with carcinoma of the rectum.

Full Text

Duke Authors

Cited Authors

  • Willett, CG

Published Date

  • January 1998

Published In

Volume / Issue

  • 8 / 1

Start / End Page

  • 24 - 29

PubMed ID

  • 9516580

International Standard Serial Number (ISSN)

  • 1053-4296

Digital Object Identifier (DOI)

  • 10.1016/s1053-4296(98)80033-7


  • eng

Conference Location

  • United States