[Psychosocial factors in coronary heart disease -- scientific evidence and recommendations for clinical practice].


Journal Article

Psychosocial risk factors like low socio-economic status, lack of social support and social isolation, chronic work or family stress, as well as negative emotions, e. g. depression and hostility, contribute significantly to the development and adverse outcome of coronary heart disease (CHD). Negative effects of psychosocial risk factors are conveyed via behavioural pathways including unhealthy lifestyle, e. g. food choice, smoking, sedentary life, inadequate utilisation of medical resources, and psychobiological mechanisms like disturbed autonomic and hormonal regulation: all these factors contribute to metabolic dysfunction and inflammatory and haemostatic processes, which are directly involved in the pathogenesis of CHD. Interventions to improve pychosocial factors are available and have demonstrated positive effects on risk factors and - at least in part - on CHD morbidity and mortality. The prevention of CHD should therefore include screening for psychosocial risk factors and adequate interventions. Recommedations for the screening of risk factors, behavioural change and further management of psychosocial risk factors in clinical practice are pointed out.

Full Text

Duke Authors

Cited Authors

  • Albus, C; De Backer, G; Bages, N; Deter, H-C; Herrmann-Lingen, C; Oldenburg, B; Sans, S; Schneiderman, N; Williams, RB; Orth-Gomer, K

Published Date

  • January 2005

Published In

Volume / Issue

  • 67 / 1

Start / End Page

  • 1 - 8

PubMed ID

  • 15672300

Pubmed Central ID

  • 15672300

International Standard Serial Number (ISSN)

  • 0941-3790

Digital Object Identifier (DOI)

  • 10.1055/s-2004-813907


  • ger

Conference Location

  • Germany