Gastrointestinal manifestations of amyloidosis.

Journal Article (Journal Article)

We reviewed gastrointestinal manifestations in 40 patients with amyloidosis. Gastrointestinal symptoms included anorexia, macroglossia, intestinal pseudo-obstruction, and altered bowel habits. Hepatomegaly was detected in eight patients, but none had clinically significant infiltrative liver disease. Mucosal friability and erosions were common endoscopic findings. Barium enema was noncontributory in the diagnosis of amyloidosis, since colonoscopy disclosed mucosal abnormalities in three of six patients with normal radiographic findings. Rectal biopsy had the highest diagnostic yield, followed by duodenal, gastric, and colonic biopsies.

Full Text

Duke Authors

Cited Authors

  • Lee, JG; Wilson, JA; Gottfried, MR

Published Date

  • February 1994

Published In

Volume / Issue

  • 87 / 2

Start / End Page

  • 243 - 247

PubMed ID

  • 8115892

International Standard Serial Number (ISSN)

  • 0038-4348

Digital Object Identifier (DOI)

  • 10.1097/00007611-199402000-00019


  • eng

Conference Location

  • United States