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Increased ectopic action potential generation accompanies epileptogenesis in vitro.

Publication ,  Journal Article
Stasheff, SF; Wilson, WA
Published in: Neuroscience letters
March 1990

We studied changes in the characteristics of action potentials of CA3 pyramidal cells accompanying electrographic seizure (EGS) induction, using an in vitro model similar to kindling. We found an increased propensity to fire action potentials which lack EPSPs or other triggering depolarizing potentials. Such 'baseline spikes' appear to be initiated at a site electrically distant from the soma.

Published In

Neuroscience letters

DOI

EISSN

1872-7972

ISSN

0304-3940

Publication Date

March 1990

Volume

111

Issue

1-2

Start / End Page

144 / 150

Related Subject Headings

  • In Vitro Techniques
  • Hippocampus
  • Epilepsy
  • Electric Stimulation
  • Animals
  • Action Potentials
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3101 Biochemistry and cell biology
  • 1702 Cognitive Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Stasheff, S. F., & Wilson, W. A. (1990). Increased ectopic action potential generation accompanies epileptogenesis in vitro. Neuroscience Letters, 111(1–2), 144–150. https://doi.org/10.1016/0304-3940(90)90359-h
Stasheff, S. F., and W. A. Wilson. “Increased ectopic action potential generation accompanies epileptogenesis in vitro.Neuroscience Letters 111, no. 1–2 (March 1990): 144–50. https://doi.org/10.1016/0304-3940(90)90359-h.
Stasheff SF, Wilson WA. Increased ectopic action potential generation accompanies epileptogenesis in vitro. Neuroscience letters. 1990 Mar;111(1–2):144–50.
Stasheff, S. F., and W. A. Wilson. “Increased ectopic action potential generation accompanies epileptogenesis in vitro.Neuroscience Letters, vol. 111, no. 1–2, Mar. 1990, pp. 144–50. Epmc, doi:10.1016/0304-3940(90)90359-h.
Stasheff SF, Wilson WA. Increased ectopic action potential generation accompanies epileptogenesis in vitro. Neuroscience letters. 1990 Mar;111(1–2):144–150.
Journal cover image

Published In

Neuroscience letters

DOI

EISSN

1872-7972

ISSN

0304-3940

Publication Date

March 1990

Volume

111

Issue

1-2

Start / End Page

144 / 150

Related Subject Headings

  • In Vitro Techniques
  • Hippocampus
  • Epilepsy
  • Electric Stimulation
  • Animals
  • Action Potentials
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3101 Biochemistry and cell biology
  • 1702 Cognitive Sciences