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Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking

Publication ,  Journal Article
Mathew, RJ; Wilson, WH; Melges, FT
Published in: Annals of Clinical Psychiatry
January 1, 1992

Psychological and physiological indices were monitored before and 120 minutes after smoking high- and low-potency marijuana cigarettes and a placebo cigarette in 35 physically and psychiatrically healthy normal volunteers during three separate visits to the laboratory. The psychological indices monitored consisted of temporal disintegration, depersonalization, and mood states. The psychological indices were cerebral blood flow, pulse, respiration, and end tidal carbon dioxide and carbon monoxide. Marijuana smoking, but not placebo smoking, was associated with significant temporal disintegration and depersonalization. The changes were most marked 30 minutes after smoking the high-potency cigarettes. Eighty-six percent of the subjects reported at least some temporal disintegration after high-potency marijuana. After marijuana smoking, there was also a significant increase in cerebral blood flow, respiration, pulse rate, and systolic blood pressure. Temporal disintegration was found to be most closely associated with depersonalization, confusion, and intoxication.

Duke Scholars

Published In

Annals of Clinical Psychiatry

DOI

ISSN

1040-1237

Publication Date

January 1, 1992

Volume

4

Issue

4

Start / End Page

235 / 245

Related Subject Headings

  • Psychiatry
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Mathew, R. J., Wilson, W. H., & Melges, F. T. (1992). Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking. Annals of Clinical Psychiatry, 4(4), 235–245. https://doi.org/10.3109/10401239209150455
Mathew, R. J., W. H. Wilson, and F. T. Melges. “Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking.” Annals of Clinical Psychiatry 4, no. 4 (January 1, 1992): 235–45. https://doi.org/10.3109/10401239209150455.
Mathew RJ, Wilson WH, Melges FT. Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking. Annals of Clinical Psychiatry. 1992 Jan 1;4(4):235–45.
Mathew, R. J., et al. “Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking.” Annals of Clinical Psychiatry, vol. 4, no. 4, Jan. 1992, pp. 235–45. Scopus, doi:10.3109/10401239209150455.
Mathew RJ, Wilson WH, Melges FT. Temporal disintegration and its psychological and physiological correlates: Changes in the experience of time after marijuana smoking. Annals of Clinical Psychiatry. 1992 Jan 1;4(4):235–245.
Journal cover image

Published In

Annals of Clinical Psychiatry

DOI

ISSN

1040-1237

Publication Date

January 1, 1992

Volume

4

Issue

4

Start / End Page

235 / 245

Related Subject Headings

  • Psychiatry
  • 1103 Clinical Sciences