Chronicity and a low anteroposterior gradient of cerebral blood flow in schizophrenia.

Journal Article (Journal Article)

Regional cerebral blood flow (CBF) was measured with the 133xenon inhalation technique in 27 patients with schizophrenia of less than 5 years' duration and in 27 patients with schizophrenia of more than 12 years' duration, under resting conditions. Similar measurements were also performed in 54 normal control subjects matched for age and sex. Patients with schizophrenia of long duration had lower anteroposterior gradients of CBF than patients with schizophrenia of short duration and matched control subjects. Covarying out age and end-tidal levels of CO2 did not alter the results.

Full Text

Duke Authors

Cited Authors

  • Mathew, RJ; Wilson, WH

Published Date

  • February 1990

Published In

Volume / Issue

  • 147 / 2

Start / End Page

  • 211 - 213

PubMed ID

  • 2301662

International Standard Serial Number (ISSN)

  • 0002-953X

Digital Object Identifier (DOI)

  • 10.1176/ajp.147.2.211


  • eng

Conference Location

  • United States