Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia.
Publication
, Journal Article
Mathew, RJ; Wilson, WH
Published in: Acta Psychiatr Scand
June 1990
Carbon dioxide (CO2) is a potent cerebrovasodilator; even mild changes in CO2 are associated with marked changes in cerebral blood flow (CBF). We measured CBF before and after 5% CO2 inhalation in 19 medicated patients with schizophrenia and 16 normal volunteers. Another group of 16 volunteers had 2 CBF measurements under resting conditions. Although both patients and controls showed marked CBF increase during CO2 inhalation, the CBF response was significantly less in the patients. Change in CBF per mm of CO2 was lower in the patients. The second group of controls did not show significant differences between the 2 resting CBF measurements.
Duke Scholars
Published In
Acta Psychiatr Scand
DOI
ISSN
0001-690X
Publication Date
June 1990
Volume
81
Issue
6
Start / End Page
497 / 506
Location
United States
Related Subject Headings
- Xenon Radioisotopes
- Sex Factors
- Schizophrenic Psychology
- Schizophrenia
- Regional Blood Flow
- Psychiatry
- Neurocognitive Disorders
- Male
- Humans
- Homeostasis
Citation
APA
Chicago
ICMJE
MLA
NLM
Mathew, R. J., & Wilson, W. H. (1990). Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia. Acta Psychiatr Scand, 81(6), 497–506. https://doi.org/10.1111/j.1600-0447.1990.tb05488.x
Mathew, R. J., and W. H. Wilson. “Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia.” Acta Psychiatr Scand 81, no. 6 (June 1990): 497–506. https://doi.org/10.1111/j.1600-0447.1990.tb05488.x.
Mathew RJ, Wilson WH. Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia. Acta Psychiatr Scand. 1990 Jun;81(6):497–506.
Mathew, R. J., and W. H. Wilson. “Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia.” Acta Psychiatr Scand, vol. 81, no. 6, June 1990, pp. 497–506. Pubmed, doi:10.1111/j.1600-0447.1990.tb05488.x.
Mathew RJ, Wilson WH. Cerebral blood flow responses to inhaled carbon dioxide in schizophrenia. Acta Psychiatr Scand. 1990 Jun;81(6):497–506.
Published In
Acta Psychiatr Scand
DOI
ISSN
0001-690X
Publication Date
June 1990
Volume
81
Issue
6
Start / End Page
497 / 506
Location
United States
Related Subject Headings
- Xenon Radioisotopes
- Sex Factors
- Schizophrenic Psychology
- Schizophrenia
- Regional Blood Flow
- Psychiatry
- Neurocognitive Disorders
- Male
- Humans
- Homeostasis