The relationship between retinal vessel tortuosity, diameter, and transmural pressure.


Journal Article

Increases in retinal vein tortuosity are thought to be caused by increases in vascular transmural pressure. We have attempted to determine the relationship between retinal vessel tortuosity, diameter, and transmural pressure by examining the effects of changes in transmural pressure on latex tubes with fixed ends. As the transmural pressure is raised, tube diameter increases, but tortuosity does not begin increasing until a critical pressure is reached. Above the critical pressure, tortuosity increases more rapidly than diameter. Our results support the above hypothesis and also suggest that at high transmural pressures, retinal vessel tortuosity is a more sensitive indicator than is the diameter of changes in retinal venous transmural pressure, but diameter is more sensitive than tortuosity at lower pressures.

Full Text

Cited Authors

  • Kylstra, JA; Wierzbicki, T; Wolbarsht, ML; Landers, MB; Stefansson, E

Published Date

  • January 1, 1986

Published In

Volume / Issue

  • 224 / 5

Start / End Page

  • 477 - 480

PubMed ID

  • 3758696

Pubmed Central ID

  • 3758696

Electronic International Standard Serial Number (EISSN)

  • 1435-702X

International Standard Serial Number (ISSN)

  • 0721-832X

Digital Object Identifier (DOI)

  • 10.1007/bf02173368


  • eng