Increased retinal oxygen supply following pan-retinal photocoagulation and vitrectomy and lensectomy.

Journal Article

Panretinal photocoagulation as well as vitrectomy are the main treatment modalities for diabetic and other proliferative retinopathies. We show that both treatments introduce a new source of oxygen to the inner retina and propose that their efficacy in controlling the retinopathy results from their effect on the oxygenation of the inner retina. Panretinal photocoagulation reduces the oxygen consumption of the outer retina and allows more oxygen to diffuse to the inner retina from the choroid. Vitrectomy/lensectomy on the other hand allows aqueous humor to flow back to the retina and give oxygen to the inner retina which normally has a lower PO2 than aqueous humor. This causes the PO2 in aqueous humor to fall.

Full Text

Cited Authors

  • Stefansson, E; Landers, MB; Wolbarsht, ML

Published Date

  • 1981

Published In

Volume / Issue

  • 79 /

Start / End Page

  • 307 - 334

PubMed ID

  • 7200671

International Standard Serial Number (ISSN)

  • 0065-9533

Language

  • eng

Conference Location

  • United States