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The influence of x-ray energy on lung dose uniformity in total-body irradiation.

Publication ,  Journal Article
Ekstrand, K; Greven, K; Wu, Q
Published in: Int J Radiat Oncol Biol Phys
July 15, 1997

PURPOSE: In this study we examine the influence of x-ray energy on the uniformity of the dose within the lung in total-body irradiation treatments in which partial transmission blocks are used to control the lung dose. METHODS AND MATERIALS: A solid water phantom with a cork insert to simulate a lung was irradiated by x-rays with energies of either 6, 10, or 18 MV. The source to phantom distance was 3.9 meters. The cork insert was either 10 cm wide or 6 cm wide. Partial transmission blocks with transmission factors of 50% were placed anterior to the cork insert. The blocks were either 8 or 4 cm in width. Kodak XV-2 film was placed in the midline of the phantom to record the dose. Midplane dose profiles were measured with a densitometer. RESULTS: For the 10 cm wide cork insert the uniformity of the dose over 80% of the block width varied from 6.6% for the 6 MV x-rays to 12.2% for the 18 MV x-rays. For the 6 cm wide cork insert the uniformity was comparable for all three x-ray energies, but for 18 MV the central dose increased by 9.4% compared to the 10 cm wide insert. CONCLUSION: Many factors must be considered in optimizing the dose for total-body irradiation. This study suggests that for AP/PA techniques lung dose uniformity is superior with 6 MV irradiation. The blanket recommendation that the highest x-ray energy be used in TBI is not valid for all situations.

Duke Scholars

Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

July 15, 1997

Volume

38

Issue

5

Start / End Page

1131 / 1136

Location

United States

Related Subject Headings

  • X-Rays
  • Whole-Body Irradiation
  • Radiation Dosage
  • Phantoms, Imaging
  • Oncology & Carcinogenesis
  • Lung
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ekstrand, K., Greven, K., & Wu, Q. (1997). The influence of x-ray energy on lung dose uniformity in total-body irradiation. Int J Radiat Oncol Biol Phys, 38(5), 1131–1136. https://doi.org/10.1016/s0360-3016(97)00286-1
Ekstrand, K., K. Greven, and Q. Wu. “The influence of x-ray energy on lung dose uniformity in total-body irradiation.Int J Radiat Oncol Biol Phys 38, no. 5 (July 15, 1997): 1131–36. https://doi.org/10.1016/s0360-3016(97)00286-1.
Ekstrand K, Greven K, Wu Q. The influence of x-ray energy on lung dose uniformity in total-body irradiation. Int J Radiat Oncol Biol Phys. 1997 Jul 15;38(5):1131–6.
Ekstrand, K., et al. “The influence of x-ray energy on lung dose uniformity in total-body irradiation.Int J Radiat Oncol Biol Phys, vol. 38, no. 5, July 1997, pp. 1131–36. Pubmed, doi:10.1016/s0360-3016(97)00286-1.
Ekstrand K, Greven K, Wu Q. The influence of x-ray energy on lung dose uniformity in total-body irradiation. Int J Radiat Oncol Biol Phys. 1997 Jul 15;38(5):1131–1136.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

ISSN

0360-3016

Publication Date

July 15, 1997

Volume

38

Issue

5

Start / End Page

1131 / 1136

Location

United States

Related Subject Headings

  • X-Rays
  • Whole-Body Irradiation
  • Radiation Dosage
  • Phantoms, Imaging
  • Oncology & Carcinogenesis
  • Lung
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
  • 0299 Other Physical Sciences