Apples to origins: identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells.

Journal Article (Journal Article)

The mechanisms whereby medulloblastoma stem cells coordinate tumor propagation are poorly understood. Using microarray analysis, Corno and colleagues draw parallels and distinctions between medulloblastoma stem cells from the Ptch(+/-) mouse and normal neural stem cells, identifying Ebf3 as a cancer stem cell-specific transcript critical for tumor growth.

Full Text

Duke Authors

Cited Authors

  • Wortham, M; Yan, H

Published Date

  • June 2012

Published In

Volume / Issue

  • 2 / 6

Start / End Page

  • 492 - 494

PubMed ID

  • 22684456

Pubmed Central ID

  • PMC3375910

Electronic International Standard Serial Number (EISSN)

  • 2159-8290

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.CD-12-0182


  • eng

Conference Location

  • United States