Snapshot of the allele-specific variation in human gene expression.

Journal Article

The analysis of gene differential expression is complicated by the potentially subtle differences associated with alterations in a single allele as well as by variations between individuals that arise from environmental or physiological factors. To circumvent these analytic problems, a method, named allele-specific differential expression analysis, was developed to compare the relative expression levels of two alleles of the same gene within the same cellular sample. The studies of allele-specific expression revealed that differential expression is relatively common in the human population.

Full Text

Duke Authors

Cited Authors

  • Yan, H

Published Date

  • 2005

Published In

Volume / Issue

  • 311 /

Start / End Page

  • 31 - 38

PubMed ID

  • 16100397

Pubmed Central ID

  • 16100397

International Standard Serial Number (ISSN)

  • 1064-3745

Digital Object Identifier (DOI)

  • 10.1385/1-59259-957-5:031


  • eng

Conference Location

  • United States