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Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.

Publication ,  Journal Article
Yang, C-H; Rumpf, S; Xiang, Y; Gordon, MD; Song, W; Jan, LY; Jan, Y-N
Published in: Neuron
February 26, 2009

Mating induces changes in the receptivity and egg-laying behavior in Drosophila females, primarily due to a peptide pheromone called sex peptide which is transferred with the sperm into the female reproductive tract during copulation. Whereas sex peptide is generally believed to modulate fruitless-GAL4-expressing neurons in the central nervous system to produce behavioral changes, we found that six to eight sensory neurons on the reproductive tract labeled by both ppk-GAL4 and fruitless-GAL4 can sense sex peptide to control the induction of postmating behaviors. In these sensory neurons, sex peptide appears to act through Pertussis toxin-sensitive G proteins and suppression of protein kinase A activity to reduce synaptic output. Our results uncover a neuronal mechanism by which sex peptide exerts its control over reproductive behaviors in Drosophila females.

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Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

February 26, 2009

Volume

61

Issue

4

Start / End Page

519 / 526

Location

United States

Related Subject Headings

  • Sodium Channels
  • Signal Transduction
  • Sexual Behavior, Animal
  • Potassium Channels, Inwardly Rectifying
  • Phenotype
  • Neurology & Neurosurgery
  • Male
  • Immunohistochemistry
  • Heterotrimeric GTP-Binding Proteins
  • Female
 

Citation

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Yang, C.-H., Rumpf, S., Xiang, Y., Gordon, M. D., Song, W., Jan, L. Y., & Jan, Y.-N. (2009). Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron, 61(4), 519–526. https://doi.org/10.1016/j.neuron.2008.12.021
Yang, Chung-Hui, Sebastian Rumpf, Yang Xiang, Michael D. Gordon, Wei Song, Lily Y. Jan, and Yuh-Nung Jan. “Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.Neuron 61, no. 4 (February 26, 2009): 519–26. https://doi.org/10.1016/j.neuron.2008.12.021.
Yang C-H, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, et al. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26;61(4):519–26.
Yang, Chung-Hui, et al. “Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.Neuron, vol. 61, no. 4, Feb. 2009, pp. 519–26. Pubmed, doi:10.1016/j.neuron.2008.12.021.
Yang C-H, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, Jan Y-N. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26;61(4):519–526.
Journal cover image

Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

February 26, 2009

Volume

61

Issue

4

Start / End Page

519 / 526

Location

United States

Related Subject Headings

  • Sodium Channels
  • Signal Transduction
  • Sexual Behavior, Animal
  • Potassium Channels, Inwardly Rectifying
  • Phenotype
  • Neurology & Neurosurgery
  • Male
  • Immunohistochemistry
  • Heterotrimeric GTP-Binding Proteins
  • Female