Diverse proteins homologous to inositol monophosphatase.


Journal Article

Bovine inositol monophosphatase (IMP) and several homologous proteins were found to share two sequence motifs with bovine inositol polyphosphate 1-phosphatase (IPP). These motifs may correspond to binding sites within IMP and IPP for inositol phosphates or for lithium, since both substances are bound by these proteins. This suggests that the proteins homologous to IMP, which have diverse biological roles but whose function is not clear, may act by enhancing the synthesis or degradation of phosphorylated compounds.

Full Text

Duke Authors

Cited Authors

  • Neuwald, AF; York, JD; Majerus, PW

Published Date

  • December 2, 1991

Published In

Volume / Issue

  • 294 / 1-2

Start / End Page

  • 16 - 18

PubMed ID

  • 1660408

Pubmed Central ID

  • 1660408

International Standard Serial Number (ISSN)

  • 0014-5793

Digital Object Identifier (DOI)

  • 10.1016/0014-5793(91)81332-3


  • eng

Conference Location

  • England