Quantitative analysis of the spatiotemporal dynamics of a synthetic predator-prey ecosystem.

Journal Article (Journal Article)

A major focus in synthetic biology is the rational design and implementation of gene circuits to control dynamics of individual cells and, increasingly, cellular populations. Population-level control is highlighted in recent studies which attempt to design and implement synthetic ecosystems (or engineered microbial consortia). On the one hand, these engineered systems may serve as a critical technological foundation for practical applications. On the other hand, they may serve as well-defined model systems to examine biological questions of broad relevance. Here, using a synthetic predator-prey ecosystem as an example, we illustrate the basic experimental techniques involved in system implementation and characterization. By extension, these techniques are applicable to the analysis of other microbial-based synthetic or natural ecosystems.

Full Text

Duke Authors

Cited Authors

  • Payne, S; Smith, RP; You, L

Published Date

  • January 2012

Published In

Volume / Issue

  • 813 /

Start / End Page

  • 315 - 330

PubMed ID

  • 22083751

Electronic International Standard Serial Number (EISSN)

  • 1940-6029

International Standard Serial Number (ISSN)

  • 1064-3745

Digital Object Identifier (DOI)

  • 10.1007/978-1-61779-412-4_19


  • eng