An isolated perfused rat lung preparation.

Journal Article (Journal Article)

An isolated perfused rat lung preparation (IPL) is described and its physiologic status is evaluated. The evaluation includes light and electron microscopy after perfusion and estimations of substrate utilization. ATP content, lactate production, and incorporation of glucose carbons into lipids and CO2. It is concluded that the IPL is useful for short-term metabolic and physiologic experiments and offers some unique advantages in evaluating effects of reactive gases upon lung function.

Full Text

Duke Authors

Cited Authors

  • Young, SL

Published Date

  • August 1, 1976

Published In

Volume / Issue

  • 16 /

Start / End Page

  • 61 - 66

PubMed ID

  • 1017421

Pubmed Central ID

  • PMC1475221

International Standard Serial Number (ISSN)

  • 0091-6765

Digital Object Identifier (DOI)

  • 10.1289/ehp.761661


  • eng

Conference Location

  • United States